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The stereoselective synthesis of the C10-C24 fragment of (+)-cannabisativine has been achieved. The key steps involved in this strategy are the Sharpless asymmetric dihydroxylation, the diastereoselective allylation of an imine, and the ring closing metathesis (RCM).
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Reference:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI