Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Recommanded Product: 4-Bromo-2,2′-bipyridine, Which mentioned a new discovery about 14162-95-9
In order to apply boronic acid-saccharide interactions to the chiroselective synthesis of Delta- and Lambda-[CoIII(bpy)3]3+ saccharide-binding ligands, 2,2?-bipyridine-4-boronic acid (bpymb) and 2,2?-bipyridine-4,4?-diboronic acid (bpydb) were newly synthesized. It was shown that most D-saccharides form cyclic 1:1 complexes with bpydb to afford the CD-active species. The positive exciton coupling band implies that two pyridine rings are twisted in a clockwise direction ((R)-chirality). In contrast, such a CD-active species was not yielded from bpymb. The treatment of the bpydb-D-saccharide complexes with Co(OAc)2 gave the substitution-active [CoII(bpyba)3]4–saccharide complexes, which were oxidized to the substitution-inactive [CoIII(bpyba)3]3–saccharide complexes. In this stage, the Delta vs. Lambda ratio was fixed. The complexes were converted to [CoIII(bpy)]3+ by treatment with AgNO3 and the e.e. was determined by comparison with authentic Delta- or Lambda-[CoIII(bpy)]3+. The Delta-isomer was obtained in excess from most D-saccharides but the Lambda-isomer was also obtained from D-fructose and D-fucose. At 4C, the largest e.e. for bpydb was attained with D-glucose (47% e.e.; Delta excess). Under the same reaction conditions the bpymb + D-glucose system gave 16% e.e. (Delta excess). The e.e. of the bpydb + D-glucose system increased with lowering the reaction temperature and at -25C it reached 79% e.e. The foregoing results clearly establish that the saccharide-templated synthesis is useful as a new concept for the preparation of chiral tris(2,2?-bipyridine)-metal complexes. Furthermore, the Delta vs. Lambda equilibrium can be shifted in either direction by the selection of saccharide enantiomers.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Recommanded Product: 4-Bromo-2,2′-bipyridine, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 14162-95-9
Reference：
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI