Application of 72-19-5, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 72-19-5, Name is H-Thr-OH, SMILES is N[C@@H]([C@H](O)C)C(O)=O, belongs to catalyst-ligand compound. In a article, author is Li, Dan, introduce new discover of the category.
Desymmetrization Process by Mg(II)-Catalyzed Intramolecular Vinylogous Michael Reaction
Chiral magnesium catalyzed intramolecular vinylogous Michael reaction of novel cyclohexadienones via a desymmetrization process is reported. (R)-BINOL derived ligand and an achiral amide were employed in the current in situ generated magnesium catalyst, giving the corresponding hydrogenated benzofuranone skeletons in good to excellent enantioselectivities with high yields. This simple and efficient strategy could be utilized for the synthesis of aromatized alpha,beta-unsaturated ester and Br-substituted hydrogenated benzofuranone in good yields under mild conditions.
Application of 72-19-5, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 72-19-5.
Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI