《Controllable Si-C Bond Activation Enables Stereocontrol in the Palladium-Catalyzed [4+2] Annulation of Cyclopropenes with Benzosilacyclobutanes》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Wang, Xing-Ben; Zheng, Zhan-Jiang; Xie, Jia-Le; Gu, Xing-Wei; Mu, Qiu-Chao; Yin, Guan-Wu; Ye, Fei; Xu, Zheng; Xu, Li-Wen. Product Details of 51364-51-3 The article mentions the following:
A novel and unusual Pd-catalyzed [4+2] annulation of cyclopropenes with benzosilacyclobutanes is reported. This reaction occurred through chemoselective Si-C(sp2) bond activation in synergy with ring expansion/insertion of cyclopropenes to form new C(sp2)-C(sp3) and Si-C(sp3) bonds. An array of previously elusive bicyclic skeleton with high strain, silabicyclo[4.1.0]heptanes, were formed in good yields with excellent diastereoselectivity under mild conditions. An asym. version of the reaction with a chiral phosphoramidite ligand furnished a variety of chiral bicyclic silaheterocycle derivatives with good enantioselectivity (up to 95.5:4.5 er). Owing to the mild reaction conditions, the good stereoselectivity profile, and the ready availability of the functionalized precursors, this process constitutes a useful and straightforward strategy for the synthesis of densely functionalized silacycles. The experimental part of the paper was very detailed, including the reaction process of Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3Product Details of 51364-51-3)
Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3) is the most widely used PdO precursor complex in synthesis and catalysis, in particular as a catalyst for various coupling reactions. Product Details of 51364-51-3 It also used for palladium-catalyzed one-pot synthesis of tricyclic indolines, in the Suzuki-Miyaura coupling of 2-pyridyl nucleophiles and cross-coupling of aryl halides with aryl boronic acids.
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI