The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 96556-05-7, Name is 1,4,7-Trimethyl-1,4,7-triazonane, SMILES is C1CN(CCN(CCN1C)C)C, in an article , author is Wu, Lianqian, once mentioned of 96556-05-7, Application In Synthesis of 1,4,7-Trimethyl-1,4,7-triazonane.
Anionic Bisoxazoline Ligands Enable Copper-Catalyzed Asymmetric Radical Azidation of Acrylamides
Asymmetric radical azidation for the synthesis of chiral alkylazides remains a tremendous challenge in organic synthesis. We report here an unprecedented highly enantioselective radical azidation of acrylamides catalyzed by 1 mol % of a copper catalyst. The substrates were converted to the corresponding alkylazides in high yield with good-to-excellent enantioselectivity. Notably, employing an anionic cyano-bisoxazoline (CN-Box) ligand is crucial to generate a monomeric Cu-II azide species, rather than a dimeric Cu-II azide intermediate, for this highly enantioselective radical azidation.
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Reference:
Metal catalyst and ligand design,
,Ligand Template Strategies for Catalyst Encapsulation – NCBI