The author of 《Evaluation of 5-[18F]fluoro-2′-deoxycytidine as a tumor imaging agent: A comparison of [18F]FdUrd, [18F]FLT and [18F]FDG》 were Yu, Hung-Man; Chiu, Ching-Hung; Chen, Wei-Ting; Wu, Chi-Han; Lin, Pei-Yao; Huang, Ya-Yao; Chen, Jyun-Hong; Tzen, Kai-Yuan; Shiue, Chyng-Yann; Lin, Wuu-Jyh. And the article was published in Applied Radiation and Isotopes in 2019. Recommanded Product: Tris(dibenzylideneacetone)dipalladium(0) The author mentioned the following in the article:
One of the hallmarks of cancer is increased cell proliferation. Measurements of cell proliferation by estimation of DNA synthesis with several radiolabeled nucleosides have been tested to assess tumor growth. This study evaluated a radiofluorinated deoxycytidine analog, 5-[18F]fluoro-2′-deoxycytidine ([18F]FdCyd), as a proliferation probe and compared it with 5-[18F]fluoro-2′-deoxyuridine ([18F]FdUrd), 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT), and [18F]fluorodeoxyglucose ([18F]FDG) in a tumor-bearing mouse model. [18F]FdCyd was synthesized from two precursors by direct electrophilic substitution. The serum stability and partition coefficient of [18F]FdCyd were evaluated in vitro. Positron emission topog. (PET) imaging of Lewis lung carcinoma (LLC)-bearing mice with [18F]FdCyd, [18F]FdUrd, [18F]FLT, and [18F]FDG were evaluated. [18F]FdCyd was stable in mouse serum and normal saline for up to 4 h. With all radiotracers except [18F]FLT, PET can clearly delineate the tumor lesion. [18F]FdCyd and [18F]FdUrd showed high accumulation in the liver and kidney. The SUV and tumor-to-muscle (T/M) ratios derived from PET imaging of the radiotracers were [18F]FDG > [18F]FdCyd > [18F]FdUrd > [18F]FLT. In addition to this study using Tris(dibenzylideneacetone)dipalladium(0), there are many other studies that have used Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3Recommanded Product: Tris(dibenzylideneacetone)dipalladium(0)) was used in this study.
Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3) is the most widely used PdO precursor complex in synthesis and catalysis, in particular as a catalyst for various coupling reactions. Recommanded Product: Tris(dibenzylideneacetone)dipalladium(0) It is used as a catalyst precursor for palladium-catalyzed carbon-nitrogen bond formation, conversion of aryl chlorides, triflates and nonaflates to nitroaromatics.
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI