《Palladium-Catalyzed Asymmetric [8+2] Dipolar Cycloadditions of Vinyl Carbamates and Photogenerated Ketenes》 was written by Zhang, Qun-Liang; Xiong, Qin; Li, Miao-Miao; Xiong, Wei; Shi, Bin; Lan, Yu; Lu, Liang-Qiu; Xiao, Wen-Jing. Synthetic Route of C51H42O3Pd2 And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:
Higher-order cycloadditions, particularly [8+2] cycloadditions, are a straightforward and efficient strategy for constructing significant medium-sized architectures. Typically, configuration-restrained conjugated systems were used as 8π-components for higher-order concerted cycloadditions However, for this reason, 10-membered monocyclic skeletons have never been constructed via catalytic asym. [8+2] cycloaddition with high peri- and stereoselectivity. Here, the authors accomplished an enantioselective [8+2] dipolar cycloaddition via the merger of visible-light activation and asym. palladium catalysis. This protocol provides a new route to 10-membered monocyclic architectures bearing chiral quaternary stereocenters with high chemo-, peri-, and enantioselectivity. The success of this strategy relied on the facile in situ generation of Pd-containing 1,8-dipoles and their enantioselective trapping by ketene dipolarophiles, which were formed in situ via a photo-Wolff rearrangement. The results came from multiple reactions, including the reaction of Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3Synthetic Route of C51H42O3Pd2)
Tris(dibenzylideneacetone)dipalladium(0)(cas: 51364-51-3) is used in the preparation of semiconducting polymers processed from nonchlorinated solvents into high performance thin film transistors.Synthetic Route of C51H42O3Pd2It is used as catalyst for the synthesis of epoxides, alpha-arylation of ketones, in combination with BINAP for the asymmetric heck arylation of olefins, site-selective benzylic sp3 palladium-catalyzed direct arylation and homoallylic diamination of terminal olefins.
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI